Renal citrate metabolism and urinary citrate excretion in the infant rat
نویسندگان
چکیده
منابع مشابه
The urinary excretion of citrate in uranium-poisoned rats.
The increased urinary excretion of citrate following administration of sodium bicarbonate has been noted by many investigators (l-9). During the course of work on the effect of uranium on various metabolic processes we wished to ascertain whether the kidney poisoned by uranium would excrete citrate to the same extent that a normal kidney does after administration of sodium bicarbonate. Surprisi...
متن کاملInhibition of Urine Citrate Excretion
We have previously observed that the urinary excretion of citrate is reduced to low levels in rats treated with the carbonic anhydrase inhibitor, acetazoleamide (Diamox®g) (1). This first experiment was prompted by the fact that the elevated serum chloride and decreased serum bicar-. bonate concentrations, and the fixation of the urine pH at approximately 7 or above following administration of ...
متن کاملUltrafiltrable serum citrate and the relationship between serum and urinary citrate results in controls and renal calcium stone formers.
The total and ultrafiltrable citrate of serum were measured in healthy controls, and in patients with calcium-containing kidney stones classified into the various calciuria types (normocalciuria, renal, absorptive, resorptive hypercalciuria). The total citrate in two subgroups (normocalciuria, renal hypercalciuria) was significantly higher than in controls. Two independent analyses showed a mea...
متن کاملThe Role of Lithium Carbonate and Lithium Citrate in Regulating Urinary Citrate Level and Preventing Nephrolithiasis
BACKGROUND AND PURPOSE Urinary Citrate is an inhibitor of Calcium oxalate stone formation. It is reabsorbed in the proximal kidney through sodium dicarboxylate co-transporters (NaDC-1, NaDC-3) present in the renal tubular epithelium. Lithium (Li) is a known potent inhibitor of these transporters. We investigated the effect of lithium carbonate (LiC) and lithium citrate (LiCit) in regulating uri...
متن کاملCitrate transport and metabolism in mammalian cells
Maria E. Mycielska,* Ameet Patel, Nahit Rizaner, Maciej P. Mazurek, Hector Keun, Anup Patel, Vadivel Ganapathy, and Mustafa B. A. Djamgoz 1 Division of Cell and Molecular Biology, Neuroscience Solutions to Cancer Research Group, Sir Alexander Fleming Building, Imperial College London, South Kensington Campus, London SW7 2AZ, UK Department of Biochemistry and Molecular Biology, Medical College o...
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ژورنال
عنوان ژورنال: Kidney International
سال: 2000
ISSN: 0085-2538
DOI: 10.1046/j.1523-1755.2000.057003891.x